Species: Mouse Genes: Gba1 Modification: Gba1: Conditional Knock-out Disease Relevance: Parkinson's Disease Strain Name: B6.129-Gba1 tm1Clk /J Genetic Background: Backcrossed 11 generations to ...
This transgenic mouse model expresses a floxed ATPase type 13A2 (Atp13a2) gene, with loxP sites flanking exons 2 to 3 (The Jackson Laboratory). The ATP13A2 protein is a transmembrane lysosomal ATPase ...
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