Biological shield can prevent skin cancer cells from transforming into aggressive metastatic forms

A new study has identified a molecular guardian that keeps skin cells from forgetting what they are and transforming into ...

This protein-engineering breakthrough generates over 10M data points and turbocharges AI in just three days

Protein engineering is a field primed for artificial intelligence research. Each protein is made up of amino acids; to ...

A major cancer protein hijacks RNA editing, exposing a new weakness in prostate tumors

Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new ...

SK Life Science Labs to Present New Preclinical Data on Targeted Protein Degradation at AACR Annual Meeting 2026

Three posters accepted at AACR 2026 highlighting SK Life Science Labs' targeted protein degradation pipeline -- Programs featured: selective p300 and PRMT5 degraders -- p300 degrader data demonstrate: ...
Johns Hopkins Medicine

Mini Brainlike Structures Grown in Lab May Help Scientists Treat Diagnose and Stage Alzheimers Disease

The Johns Hopkins team set out to analyze mini models of the hindbrain, the brain’s command center in the back of the skull ...
AHA/ASA Journals

Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
Frontiers

Novel Cell-Based Assays and Screening Technologies in Drug Discovery

Cell-based assay innovation is reshaping how we discover, validate, and de-risk therapeutic candidates across disease areas. This Research Topic invites ...