Stem cell embryo model grows yolk sac without hypoblasts or gene editing

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like ...
eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
eLife

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...
The Scientist

The Long Road to Complete the Human Genome Project

Explore the decades-long journey to map the full human genome, from early breakthroughs to the first complete, gapless DNA ...