CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing.

Welcome to the Department of Computer Science at the University of Alabama at Birmingham. The department provides an excellent learning environment for both undergraduate and graduate students, and is ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double ...

A novel all-optical method, laser optothermal nanobomb (LOTB), is proposed to efficiently flatten nanobubbles in two-dimensional materials. This non-contact technique reduces surface roughness by over ...