When bacteria cells replicate, they do so a little differently than human cells do. They don’t undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

University of Oxford-led research finds low-dose rapamycin functions as a genomic protector in aging human immune cells, lowering DNA damage. Subscribe to our newsletter for the latest sci-tech news ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Leading Manchester United’s academy is no ordinary backroom role. The club’s heritage of developing young talent is unparalleled in English football, so whoever is tasked with running it has ...

When University of Delaware junior Nivedita Prabhu stood up to ask former New Jersey governor Chris Christie a question about political corruption at the 2024 James R. Soles lecture last fall, she was ...

Katie has a PhD in maths, specializing in the intersection of dynamical systems and number theory. She reports on topics from maths and history to society and animals. Katie has a PhD in maths, ...

Accurate genome duplication is essential for all living cells. In Escherichia coli and most other bacteria, a circular chromosome is replicated bidirectionally at high speed. Two replisomes, assembled ...

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